Alternative complement pathway assay data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture

Publication Date

2023-09-08

Start Date

2018-10-19

End Date

2018-10-26

Leet, J.K., Claunch, R.A., Richter, C.A., and Tillitt, D.E., 2023, Alternative complement pathway assay data for adult largemouth bass exposed in outdoor ponds to 17alpha-ethinylestradiol or an estrone-atrazine mixture: U.S. Geological Survey data release, https://doi.org/10.5066/P91G7KMO.

Type: Related Primary Publication

Disease outbreaks, skin lesions, fish kill events, and reproductive abnormalities have been observed in wild populations of Centrarchids in the Chesapeake Bay watershed. Occurrence of synthetic and natural hormones from wastewater treatment plants and livestock operations, pesticides from agricultural lands, and phytoestrogens have been implicated as potential causes of these adverse effects. Our objective was to investigate possible immunomodulation in adult largemouth bass (Micropterus salmoides) in response to a seasonal exposure to environmentally relevant contaminants in outdoor experimental ponds. Exposures included 17alpha-ethinylestradiol (EE2; 2.4 nanograms per liter) or a binary mixture of endocrine-active substances commonly detected in the Chesapeake Bay watershed, atrazine (5.4 micrograms per liter) and estrone (47.9 nanograms per liter). Our results can provide information on contaminants can alter immune function in an economically important fish species.

• Columbia Environmental Research Center (CERC)
• USGS Data Release Products