Landscape conservation design is an opportunity for the U.S. Fish and Wildlife Service’s National Wildlife Refuge System (NWRS) to work collaboratively with partners to develop and implement a landscape approach that ensures our priority resources will have the capacity to cope with and respond to future change. This research models patterns of climate connectivity to map linkages among protected areas that promote long-term landscape connectivity across Alaska and northwest Canada under projected climate change. Using spatial data on current land use and climate patterns, and circuit theory-based connectivity modeling approaches, this research identifies corridors that follow climate gradients and avoid human modified areas. This approach offers a flexible framework that can be adapted to address diverse conservation and stakeholder priorities.