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Dissolved pesticides were measured in weekly water samples from 100 wadeable streams across eleven states in the Midwestern U.S. during May-August, 2013, as part of the Midwest Stream Quality Assessment study conducted by the U.S. Geological Survey's (USGS) National Water Quality Assessment (NAWQA) Project. Of the 100 stream sites, 12 were urban indicator sites and the remaining 88 sites were located along an agricultural gradient of watershed land use. Twelve depth- and width-integrated samples were collected at each site within the 14-week study period. Water samples were filtered (0.7 micrometers) and analyzed for 227 pesticide compounds by direct-injection liquid chromatography with tandem mass-spectrometry,...