Filters: Tags: developmental toxicity (X)
3 results (2.7s)
Filters
Date Range
Contacts
Categories Tag Types
|
- Observations of test subjects and hatching data - Body weight, organ/tissue weights - Biomarker data (oxidative stress indicators, oxidative DNA damage, thyroid hormones, histological findings) in various tissues - Chemical residues in tissues
Categories: Data;
Tags: American kestrel (Falco sparverius),
Birds,
Contamination and Pollution,
Ecotoxicology,
Ecotoxicology,
A number of brominated flame retardants (BFRs) have been reported to interfere with the thyroid signaling pathway and cause oxidative stress in birds, yet the underlying shifts in gene expression associated with these effects remain poorly understood. In this study, we measured hepatic transcriptional responses of 31 genes in American kestrel hatchlings following in ovo exposure to one of three high-volume alternative BFRs: 1,2-bis(2,4,6-tribromophenoxy) ethane (BTPBE), bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate (TBPH), or 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EHTBB). Hatchling kestrels exhibited shifts in the expression of genes related to oxidative stress (CYP, GSTA, SOD, GPx), thyroid hormone metabolism...
Categories: Data;
Tags: American kestrel (Falco sparverius),
BTBPE,
Brominated flame retardants,
Eastern Ecological Science Center,
Genetics,
Observations of test subjects and hatching data - Body weight, organ/tissue weights Biomarker data (oxidative stress indicators, oxidative DNA damage, thyroid hormones, histological findings) in various tissues Chemical residues in tissues
Categories: Data;
Tags: American kestrel (Falco sparverius),
Brominated flame retardants,
EHTBB,
Environmental Health,
Firemaster 550,
|
![]() |