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  3. Particulate Matter Identification in Lung Tissue from Deployers, Positive, and Negative controls Using Scanning Electron Microscopy and Energy Dispersive Spectroscopy (2013-2016)
  4. Summary of the Inorganic Particle Identifications

Summary of the Inorganic Particle Identifications

Dates

Publication Date
Start Date
2013-05-01
End Date
2016-04-01

Citation

Lowers, H.A., Breit, G.N., Pillers, R.M., Meeker, G.P., and Wolf, R.E., 2016, Particulate Matter Identification in Lung Tissue from Deployers, Positive, and Negative controls Using Scanning Electron Microscopy and Energy Dispersive Spectroscopy (2013-2016): U.S. Geological Survey data release, https://dx.doi.org/10.5066/F7VX0DN5.

Summary

We developed and tested a new method for in situ characterization and distribution of inorganic particles in biopsied lung tissue from three diverse human subject groups using field emission scanning electron microscopy with an energy dispersive analyzer. The following .csv files summarize the inorganic particle identifications made in each frame of each area for each subject in the study. The In_Situ_Frame_Summary_2016-09-09_NJH***.csv is a tabulation of the phases identified in each frame. The In Situ Area Summary_2016-09-09.csv totals the number of times each phase was identified in an area of the lung tissue biopsy for each subject from the In_Situ_Frame_Summary_2016-09-09_NJH***.csv. The In Situ Subject Summary_2016-09-09.csv [...]

Contacts

Point of Contact :
Heather A Lowers
Originator :
Heather A Lowers, George N Breit, Renee M Pillers, Gregory P Meeker, Ruth E Wolf
Metadata Contact :
Heather A Lowers
Publisher :
U.S. Geological Survey
Distributor :
U.S. Geological Survey – ScienceBase

Attached Files

Click on title to download individual files attached to this item.

Particulate_Matter_Identification_in_Lung_Tissue_2013_2016_CSV.xml
Original FGDC Metadata
View 		39.24 KB
In Situ Frame Summary_2016-09-09_NJH132.csv 664 Bytes
In Situ Frame Summary_2016-09-09_NJH169.csv 3.16 KB
In Situ Frame Summary_2016-09-09_NJH212.csv 5.28 KB
In Situ Frame Summary_2016-09-09_NJH244.csv 1.42 KB
In Situ Frame Summary_2016-09-09_NJH287.csv 3.81 KB
In Situ Frame Summary_2016-09-09_NJH311.csv 2.32 KB
In Situ Frame Summary_2016-09-09_NJH389.csv 17.83 KB
In Situ Frame Summary_2016-09-09_NJH431.csv 12.9 KB
In Situ Frame Summary_2016-09-09_NJH435.csv 1.28 KB
In Situ Frame Summary_2016-09-09_NJH452.csv 7.53 KB
In Situ Frame Summary_2016-09-09_NJH456.csv 773 Bytes
In Situ Frame Summary_2016-09-09_NJH535.csv 3.85 KB
In Situ Frame Summary_2016-09-09_NJH542.csv 9.1 KB
In Situ Frame Summary_2016-09-09_NJH589.csv 6.4 KB
In Situ Frame Summary_2016-09-09_NJH613.csv 4.62 KB
In Situ Frame Summary_2016-09-09_NJH627.csv 11.83 KB
In Situ Frame Summary_2016-09-09_NJH632.csv 10.89 KB
In Situ Frame Summary_2016-09-09_NJH645.csv 7.3 KB
In Situ Frame Summary_2016-09-09_NJH746.csv 5.06 KB
In Situ Frame Summary_2016-09-09_NJH750.csv 4 KB
In Situ Frame Summary_2016-09-09_NJH765.csv 2.09 KB
In Situ Frame Summary_2016-09-09_NJH789.csv 804 Bytes
In Situ Frame Summary_2016-09-09_NJH811.csv 7.19 KB
In Situ Frame Summary_2016-09-09_NJH867.csv 885 Bytes
In Situ Frame Summary_2016-09-09_NJH873.csv 11.18 KB
In Situ Frame Summary_2016-09-09_NJH882.csv 993 Bytes
In Situ Frame Summary_2016-09-09_NJH887.csv 4.67 KB
In Situ Frame Summary_2016-09-09_NJH907.csv 4.07 KB
In Situ Frame Summary_2016-09-09_NJH916.csv 3.9 KB
In Situ Frame Summary_2016-09-09_NJH936.csv 9.53 KB
In Situ Frame Summary_2016-09-09_NJH952.csv 2.22 KB
In Situ Frame Summary_2016-09-09_NJH987.csv 2.31 KB
In Situ Frame Summary_2016-09-09_NJH998.csv 292 Bytes
Digestion Summary_2016-09-09.csv 9.85 KB
In Situ Area Summary_2016-09-09.csv 31.25 KB
In Situ Subject Summary_2016-09-09.csv 10.72 KB

Purpose

This project served to support a Department of Defense Grant lead by Dr. Cecile Rose at National Jewish Health titled Development of a Morphometric Approach to Quantification of Small Airways Disease and Particulate Matter Exposure Profiles in Lung Biopsies of Deployed US Military Personnel (Award number W81XWH-11-1-0216). The purpose of this project was to develop an in situ method to document and identify inorganic particulate matter in small sample volumes of lung biopsy sections from three study cohorts: deployed service members to Iraq and Afghanistan, a normal age- and smoking-matched control group, and an autoimmune control group. The identified phases were cataloged to assess if the relative abundance of identified phases from three study cohorts was statistically different. This data release provides a repository of images and chemistry of the identified inorganic particulate matter in a wide range of subjects that may be accessed by toxicologists, public health officials, pulmonologists, atmospheric scientists, and others interested in particulate matter in the air and body.

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